本书分为上篇、中篇和下篇三部分。上篇为阅读指导，深入浅出地介绍了巨人牛顿的一生经历，《原理》的写作背景、体系、结构和特点，简要总结了该书具体讲了什么内容，并为学生提供切实的阅读建议。中篇精选了原著的精华部分，牛顿在书中构建了一个人类有史以来最为宏伟的物理理论体系，很好地解释了当时已知的一切运动形式和现象。下篇为学习资源，包括扩展阅读、数字课程、思考题、阅读笔记。
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